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Resolve-IT Clinical Trial

Mature couple relaxing outdoors with cirrhosis illustration detail.

When was the last time you checked to see if your liver is healthy?

Nonalcoholic steatohepatitis (NASH) is a progressive liver disease that has no approved treatment and often has no symptoms. Having diabetes, high cholesterol, or obesity increases your risk for NASH. Treating and resolving NASH is vital to stopping progression to cirrhosis.

The Resolve-IT clinical trial will evaluate the efficacy of elafibranor on the resolution of nonalcoholic steatohepatitis (NASH), a form of nonalcoholic fatty liver disease.

The Resolve-IT clinical trial is a multicenter, randomized, double-blind, placebo-controlled phase III study to evaluate the efficacy and safety of elafibranor in patients with nonalcoholic steatohepatitis (NASH) and fibrosis.

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Learn More

To learn more about this clinical trial, please contact:
Cynthia Gifford-Hollingsworth, DrNP

Principal Investigator: Andres Riera, MD*

For more information, please visit

Is this Clinical Trial for You?

Study participants must be aged 18 to 75 years with biopsy-confirmed NASH and liver fibrosis at stage 1 or greater, and who are not pregnant or planning to become pregnant during the course of the study.

How the Clinical Trial Works

If you qualify for and choose to participate in the RESOLVE-IT clinical research study, your participation will last approximately 6 years. During this time, you will attend study visits where the study doctor and staff will perform study-related procedures and ask you questions about your health. These study visits will occur every 12 weeks for the first 18 months of the study. After that, you will have visits every 6 months at the study site until you complete the study.

Location of the Clinical Trial

Center for Liver, Biliary and Pancreatic Diseases
216 N Broad Street, 15th Floor
Philadelphia, PA 19102

* Physician's practice/location is independent of Drexel Medicine and Drexel University.

The information on these pages is provided for general information only and should not be used for diagnosis or treatment, or as a substitute for consultation with a physician or health care professional. If you have specific questions or concerns about your health, you should consult your health care professional.

The images being used are for illustrative purposes only; any person depicted is a model.

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